Dr. Rafat Amin

Dr. Rafat Amin


Dr. Rafat Amin


Associate Professor




Dow College of Biotechnology, Serobiology Building, 3rd Floor, DUHS, Ojha Campus


MS. Ph.D (Biotechnology), University of Tuebingen, Germany



  • • Tauqeer Bibi, Arshad Hassan, Rafat Amin, Chander Kumar, Asma Naz, Farzeen Tanwir, Fauzia Qadir, Saima Mazhar. Prevalence of periodontitis bases on ethinic disparity in Karachi, Pakistan. Journal of Xi’an Shiyou University, Natural Science Edition. (2023). 9(3)
  • •  Nadia Wajdan, Kashif Aslam, Rafat Amin, Sadaf Khan, Naseer Ahmed, Abhishek Lal, Eman M Al-Hamdan, Fahim Vohra, Tariq Abdul jabbar, Artak Heboyan. Anti-fungal efficacy of Miswak extract (Salvadora persica) and commercial denture cleaner against Candida albicans on heat cured polymethylmethacrylic denture base resin. J Appl Biomater Funct Mater. 2023 Jan-Dec;21:22808000231165666. doi: 10.1177/22808000231165666.
  • •  Iqra Rehman, Somia Gul, Mahwish Akhtar, Rafat Amin, Roquia fatima. Design, synthesis and docking studies of ciprofloxacin analogues as potential antimicrobial agents against resistant pathogens. 2024. Journal of Molecular Structure. Volume 1295, Part 2.
  • • Waldvogel E, Herbig A, Battke F, Amin R., Nentwich M, Nieselt K, Ellingsen TE, Wentzel A, Hodgson DA, Wohlleben W, Mast Y. (2011). The PII protein GlnK is a pleiotropic regulator for morphological differentiation and secondary metabolism in Streptomyces coelicolor. Appl Microbiol Biotechnol. 92: 1219-36.
  • • Iqbal, M., Mast, Y., Amin, R., Hodgson, D., Wohlleben, W., Burrroughs, N. (2012). Extracting regulator activity profiles by integration of de novo motifs and expression data: characterising key regulators of nutrient depletion responses in Streptomyces coelicolor. Nucleic Acids Research. doi: 10.1093/nar/gks205.
  • Amin R., Reuther, J., Bera, A, Wohlleben, W., Mast, Y. (2012) Novel GlnR-target gene nnaR is involved in nitrate/nitrite assimilation in Streptomyces coelicolor. Microbiology. 158: 1172-82
  • • Sola-Landa, A., Rodríguez-García, A., Amin, R., Wohlleben, W. and Martín, J. (2012). Competition between the GlnR and PhoP regulators for the glnA and amtB promoters in Streptomyces coelicolor. Nucleic Acids Research.
  • • Nawaz R., Amin R., Gul S.  and Khanani  R.  (2014). Association of Hypovitaminosis D and hypocalcemiawith Neuropsychiatric Disorders. Vol 8, No 3. jduhs.
  • Rafat Amin, Yvonne Tiffert, Yousra Ahmed, Mirita Franz-Wachtel, Boris Maèek, Wolfgang Wohlleben and Agnieszka Bera. 2016. GlnR an atypical response regulator, post-translationally modified by serine/threonine phosphorylation and N-lysine acetylation. Front. Mol. Biosci.
  • Amin R., Zaidi M. B., Bashir, S., Khanani, R., Nawaz, R., Ali, S. and Khan S. (2019) Microbial contamination levels in the drinking water and associated health risks in Karachi, Pakistan. Journal of Water, Sanitation and Hygiene for Development.  https://doi.org/10.2166/washdev.2019.147
  • • Sheikh A, Baqai N, Minhas S, Amin R. Frequency and Specificity of Red Blood Cell (RBC) Allo-immunization in Multiple Transfused Breast Cancer Patients. Liaquat National Tumor Board Journal 2019; 1(2): 19-23
  • • AbbuHazim F, Ishrat U, Fatima T, Baqai N, Amin R. Evaluating the status of vitamin 25 (OH) D levels among females of all age groups in Karachi, Pakistan. Journal of Muhammad Medical College, Mirpurkhas. 2019;10(2):55-8.
  • • Nawaz R, Gul S, Amin R, Huma T, Al Mughairbi F. Overview of schizophrenia research and treatment in Pakistan. Heliyon. 2020 Nov 1;6(11):e05545.
  • • Mehmood A, Zeb TF, Amin R, Waseem HF, Anjum F, Mahmood A, Shaikh A. Effects of Carbonated Drinks on Bone Health of Young Adults: a study conducted amongst students of Health University. Pakistan Journal of Medical & Health Science. 2020. 14(4):850
  • • Ali S, Amin R, Zeb TF, Khalid X, Ashar R, Uddin SM, Ali A, Haider MS. Formulation of a cost-effective medium to support high biomass production and improved amino acid profile of Arthrospira Palntensis. Pakistan Journal of Science. 2020 Dec 1;72(4).
  • • Khan M, Ahmed I, Farooq S, Khan S, Amin R, Ali S. Probiotic potential of Saccharomyces strains isolated from Litchi chinensis (Lychee fruit). Pakistan Journal of Pharmaceutical Sciences. 2020 Jul 1;33(4 (Supplementary)):1855-61.
  • • Khan S, Amin R, Ali S, Zeb TF, Haider MS, Tarar OM. Comparative analysis of nutritional components of different parts of Moringa Oleifera from Karachi, Pakistan. Pakistan Journal of Science. 2020 Dec 31;72(4):271.
  • • Zaheer, S., Fatima Zeb, T., Baloch, A., Amin, R., Amjad, Z., & Sheikh, A. (2020). The multifactorial burden of Type 2 Diabetes mellitus: a study from clinical settings of University Hospital, Karachi, Pakistan. International Journal of Endorsing Health Science Research (IJEHSR), 8(4), 275-287.
  • • Abid, A., Khan, H., Fatima Zeb, T., Uddin, S. M., Amin, R., Khan, S., & Ali, S. Macromolecular characterization and growth kinetics of Arthrospira platensis and Chlorella Vulgaris as affected by different media (synthetic and Anaerobic Digestor Effluent) - A comparative study. 2020. International Journal of Endorsing Health Science Research (IJEHSR), 8(4), 188-201.
  • • Amjad, Z., Shabbir, S., Mughal, A., Zeb, T., Amin, R., & Mirza, T. Effect of Ginkgo Biloba Extract (EGb 761) on Lead-induced Nephrotoxicity in Wistar Albino Rats. 2020. International Journal of Endorsing Health Science Research (IJEHSR), 8(4), 202-211.
  • • Sadaf Khan, Basma Aziz, Urooj Ishrat, Tehseen Fatima Zeb, Rafat Amin, Shaukat Ali. Comparative Evaluation of Salivary Protein Profile and Oxidative Stress Status among Smokers/ Non-Smokers. Pakistan Journal of Medical & Health Science. 2020. 14(4):755 .
  • • S Rafique, S Khan, S Ahmed, MA Qureshi, R Amin. Case-control study for assessment of factors associated with periodontitis among adults attending a university hospital in Karachi, Pakistan. jPMA. January 2021, Volume 71, Issue 1
  • • Majeed MM, Ahmed I, Roome T, Fatima T, Amin R. Association between Interleukin-1β Gene Polymorphism and Chronic Periodontitis. European Journal of Dentistry. 2021 Oct;15(04):702-6.
  • Amin R, Khan S, Zeb TF, Ali S, Baqai N, Baqai M, Shuja S. Knowledge and attitudes toward genetically modified (GM) food among health sciences university students in Karachi, Pakistan. Nutrition & Food Science. 2021 May 5.
  • • Shamim S, Gul S, Rauf A, Rashid U, Khan A, Amin R, Akhtar F. Gemifloxacin-transition metal complexes as therapeutic candidates: antimicrobial, antifungal, anti-enzymatic, and docking studies of newly synthesized complexes. Heliyon. 2022 Aug 1;8(8):e10378.