Dr. Nadia Naeem

Dr. Nadia Naeem

Name

Dr. Nadia Naeem

Designation

Assistant Professor of Pathology

Email

nadia.naeem@duhs.edu.pk

Office

Dow Research Institute of Biotechnology and Biomedical Sciences, 2nd Floor, Dow Research and Diagnostic Complex, Ojha Campus, DUHS

Qualifications

  • M.Sc.: Department of Microbiology, University of Karachi
     
  • PhD (Molecular Medicine): Dr Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi.

Research

  1. Iqbal HA, Naeem N, Haneef K, Salim A. Sulfasalazine and Chromotrope 2B reduce oxidative stress in murine bone marrow-derived mesenchymal stem cells. Molecular Biology Reports. 2023 May;50(5):4119-31.
  2. Mustafa T, Khan I, Iqbal H, Usman S, Naeem N, Faizi S, Salim A. Rutin and quercetagetin enhance the regeneration potential of young and aging bone marrow-derived mesenchymal stem cells in the rat infarcted myocardium. Mol Cell Biochem. 2023 Aug;478(8):1759-1770. doi: 10.1007/s11010-022-04628-5.
  3. Tarique S, Naeem N, Salim A, Ainuddin JA, Haneef K. The role of epigenetic modifiers in the hepatic differentiation of human umbilical cord derived mesenchymal stem cells. Biol Futur. 2022 Dec;73(4):495-502. doi: 10.1007/s42977-022-00145-0. Epub 2022 Dec 13.
  4. Rida-e-Maria Qazi IK, Haneef K, Malick TS, Naeem N, Ahmad W, Salim A, Mohsin S. Combination of mesenchymal stem cells and three-dimensional collagen scaffold preserves ventricular remodeling in rat myocardial infarction model. World Journal of Stem Cells. 2022 Aug 26;14(8):633-57.
  5. Razzaq SS, Khan I, Naeem N, Salim A, Begum S, Haneef K. Overexpression of GATA binding protein 4 and myocyte enhancer factor 2C induces differentiation of mesenchymal stem cells into cardiac-like cells. World J Stem Cells. 2022 Sep 26;14(9):700-713. doi: 10.4252/wjsc.v14.i9.700.
  6. Jabeen U, Salim A, Khan I, Naeem N, Mushtaq R. Insight into the Mechanism of Doxorubicin-induced Nephrotoxicity through Gene Expression Analysis of Oxidative Stress, Kidney Injury and Inflammation Markers. Pakistan Journal of Zoology. 2021 https://dx.doi.org/10.17582/journal.pjz/20210521070542.
  7. Haneef K, Habib R, Naeem N, Salim A. Stem Cell Factor Gene Overexpression Enhances the Fusion Potential of Rat Bone Marrow Mesenchymal Stem Cells with Cardiomyocytes. Pakistan Journal of Zoology. 2021 Dec 1;53(6):2305.
  8. Ali SR, Ahmad W, Naeem N, Salim A, Khan I. Small molecule 2'-deoxycytidine differentiates human umbilical cord-derived MSCs into cardiac progenitors in vitro and their in vivo xeno-transplantation improves cardiac function. Mol Cell Biochem. 2020;470(1-2):99-113. doi:10.1007/s11010-020-03750-6
  9. Qazi RE, Naeem N, Khan I, Qadeer Q, Shaheen F, Salim A. Effect of a dianthin G analogue in the differentiation of rat bone marrow mesenchymal stem cells into cardiomyocytes [published online ahead of print, 2020 Jul 31]. Mol Cell Biochem. 2020;10.1007/s11010-020-03855-y.doi:10.1007/s11010-020-03855-y
  10. Khalid RS, Khan I, Zaidi MB, Naeem N, Haneef K, Qazi RM, Habib R, Malick TS, Ali A, and Salim A. IL7 Over-expression Enhances Therapeutic Potential of Rat Bone Marrow Mesenchymal Stem Cells for Diabetic Wounds. Wound Repair and Regeneration, 2019, 27(3): 235-48.
  11. Fareed U, Khan I, Naeem N, Salim A. Expression Analysis of Oxidative Stress Induced Genes in Liver and Heart Tissues in Response to Doxorubicin. 2019 Pakistan Journal of Zoology.
  12. Haneef K, Ali A, Khan I, Naeem N, Jamall S, and Salim A. IL-7 Transfected Bone Marrow Mesenchymal Stem Cells Show Increased Fusion Potential in vitro and Improved Cardiac Function in vivo in Rat Model of Myocardial Infarction. Cardiovasc Ther. 2018: 19:e12479.
  13. Khan M, Perveen A, Mansuri S, Galani S, Ali MK, Aijaz S, Naeem N. The Effect of Typha Domingensis Pers. Pollen on Balb/C Mice Mimicking Local Allergic Rhinitis Like Symptoms. Pakistan Journal of Botany. 2018 Apr 1;50(2):769-74.
  14. Naeem BK, Perveen S, Naeem N, Ahmed T, Khan I, Khan I, Tahir M, Iqbal M, Naeem B. Visceral injuries in patients with blunt and penetrating abdominal trauma presenting to a tertiary care facility in Karachi, Pakistan. Cureus. 2018 Nov 17;10(11).
  15. Ali S, Farooq S, Naeem N. FINDING THE ROOT CAUSE OF FREQUENTLY PREVALENT DISEASE IN SUGARCANE FROM SOME DISEASED FIELDS OF SINDH, PAKISTAN. FUUAST Journal of Biology. 2018 Dec 18;8(2):243-7.
  16. Khan I, Ali A, Akhter MA, Naeem N, Chotani MA, Iqbal H, Kabir N, Atiq M, Salim A. Epac-Rap1- activated mesenchymal stem cells improve cardiac function in rat model of myocardial infarction. Cardiovasc Ther. 2017 Apr;35(2). doi: 10.1111/1755-5922.12248.
  17. Role of small molecules in the cardiac differentiation of mesenchymal stem cells Irfan Khan, Nadia Naeem, Anwar Ali, Asmat Salim Jan 2017 Stem Cells From Drug to Drug Discovery
  18. Khan I, Ali A, Akhter MA, Naeem N, Chotani MA, Mustafa T, Salim A. (2016) Preconditioning of mesenchymal stem cells with 2,4-dinitrophenol improves cardiac function in infarcted rats. Life Sciences. Oct 1;162:60-9. doi: 10.1016/j.lfs.2016.08.014.
  19. Usman S, Khan I, Naeem N, Iqbal H, Ali A, Usman S, Salim A. (2016) Conditioned media transdifferentiate mature fibroblasts into pancreatic beta-like cells. Life Sciences. 164:52-59
  20. Khanabdali R, Saadat A, Fazilah M, Bazli KF, Qazi RE, Khalid RS, Hasan Adli DS, Moghadamtousi SZ, Naeem N, Khan I, Salim A, Shamsuddin SA, Mohan G (2015) Promoting effect of small molecule in cardiomyogenic and neurogenic differentiation of rat bone marrow derived mesenchymal stem cells.  Rug Design, Development and Therapy, Dec 24;10:81-91
  21. Habib R., Haneef K., Naeem N., Khan I and Salim A (2015). Hypoxic stress and IL-7 gene overexpression enhance the fusion potentialof rat bone marrow mesenchymal stem cells with bovine renal epithelial cells.. Molecular and Cellular Biochemistry. 403(1 -2):125-37
  22. Ali A, Akhter MA, Haneef K, Khan I, Naeem N, Habib R, Kabir N, Salim A. (2015) Dinitrophenol modulates gene expression levels of angiogenic, cell survival and cardiomyogenic factors in bone marrow derived mesenchymal stem cells. Gene, 555, 448-457
  23. Ilyas A., Hashim Z., Naeem N., Haneef K and Zarina S (2014) The Effect of Alendronate on Proteome of Hepatocellular Carcinoma Cell Lines. International Journal of Proteomics Volume2014, Article ID 532953, 9 pages http://dx.doi.org/10.1155/2014/532953 (IF: N/A)
  24. Haneef K, Naeem N, Iqbal H, Jamall S, Kabir N, Zahid M, and Salim A. (2014) Conditioned medium enhances the fusion capability of rat bone marrow mesenchymal stem cells and cardiomyocytes. Molecular biology reports, Vol. 41, Issue 5, 3099-3112.
  25. Khan I, Ahmed N, Akhter MA, Ali A, Haneef K, , Naeem N, and Salim A. (2013) Effect of Rap1 GTPase activation and hypoxia on the gene expression pattern of cell adhesion molecules in bone marrow derived Mesenchymal stem cells. Pak. J. Biochem. Mol. Biol. Vol. 46 (1), 16-21.
  26. Naeem N, Haneef K, Kabir N, Jamall S, and Salim A. (2012) DNA demethylating agents, 5-azacytidine and zebularine potentiate the trans-differentiation of rat bone marrow mesenchymal stem cells into cardiomyocytes. Cardiovascular Therapeutics, Vol. 31, Issue 4, 201–209.
  27. Haneef K, Naeem N, Iqbal H., Jamall S, Kabir N and Salim A (2010) Gene expression pattern in rat bone marrow mesenchymal stem cells in response to hypoxia. Pak. J. Biochem. Mol. Biol. Vol. 43, 90-93.